Next-Generation Sequencing (NGS) Analysis Services

From raw data to actionable insights – empowering your research with advanced NGS solutions.

Next-Generation Sequencing (NGS) analysis services

At Origene Biosolutions, we specialize in providing comprehensive Next-Generation Sequencing (NGS) analysis services. Whether you’re working on genomics, transcriptomics, or microbiome studies, our expertise ensures accurate and reliable results that drive your research forward.

Sequence Analysis

1. Genome Analysis

  • De Novo Assembly: Construct high-quality genomes for novel organisms using cutting-edge algorithms.
  • Genome Annotation: Identify genes, regulatory elements, and functional regions within your genome.
  • Variant Calling: Detect SNPs, indels, and structural variations across samples.
  • Comparative Genomics: Compare genomes to study evolutionary relationships and functional differences.
Pharmacophore Modeling

2. Transcriptome Analysis

  • RNA-Seq Analysis: Quantify gene expression levels, identify differentially expressed genes, and discover novel transcripts.
  • Alternative Splicing: Detect and analyze splicing events to understand transcript diversity.
  • Isoform Analysis: Characterize full-length isoforms for a more complete transcriptomic picture.
  • Pathway Enrichment: Link differentially expressed genes to biological pathways and processes.
ADMET Predictions

3. Epigenomics

  • DNA Methylation Analysis: Profile genome-wide methylation patterns using bisulfite sequencing data.
  • ChIP-Seq: Study protein-DNA interactions to identify binding sites of transcription factors or histone modifications.
  • ATAC-Seq: Analyze chromatin accessibility to uncover regulatory elements.
  • Epigenetic Modifications: Link methylation or histone changes to phenotypic traits or diseases.
Hit-to-Lead Optimization

4. Microbiome and Metagenomics

  • 16S/18S/ITS rRNA Analysis: Profile bacterial, archaeal, or fungal communities with targeted sequencing.
  • Shotgun Metagenomics: Explore the functional potential and taxonomy of entire microbiomes.
  • Metatranscriptomics: Analyze the active genes and pathways within microbial communities.
  • Diversity Metrics: Calculate alpha and beta diversity to understand community structure and dynamics.
Computational Tools for Target Identification

5. Custom NGS Analysis Pipelines

  • Pipeline Design: Develop end-to-end pipelines for specialized applications.
  • Integration with Multi-Omics: Combine NGS data with proteomics, metabolomics, or other datasets.
  • Cloud and HPC Solutions: Ensure scalability for large datasets and high-throughput projects.
  • Data Visualization: Generate insightful graphs and charts for publication-ready results.

Inquiry

Why to Choose
Origene Biosolutions
for NGS Analysis?

  • Expertise in handling diverse sequencing platforms like Illumina, PacBio, and Oxford Nanopore.
  • Proven workflows for accurate, reproducible results.
  • Scalable solutions for small projects and large consortia.
  • Timely delivery with dedicated support for troubleshooting and consultation.
  • Provide in-depth analysis and biological interpretation.

From discovery to data interpretation, Origene Biosolutions is your trusted partner in NGS analysis.

Contact us today to transform your sequencing data into breakthroughs!