Resources

In-house developed bioinformatics tools and databases tailored to support research, education, and innovation in life sciences.

Resources

Origene Biosolutions offers a suite of in-house developed bioinformatics tools and databases tailored to support research, education, and innovation in life sciences. These resources are designed to address key challenges in biological data analysis, including phytochemical screening, vaccine design, sequence analysis, and molecular modeling. Built with scientific precision and practical usability in mind, our tools empower users with reliable platforms for data-driven discovery and decision-making.

Databases


MetaVault | Metabolites database

Microbial metabolite database presently holds 2,364 microbial metabolites, including their biochemical reactions and pathway links from KEGG. It integrates genomic, metabolomic, and spectral information for a comprehensive view of microbial metabolites. The resource supports exploration of microbial biosynthesis, metabolic engineering, and natural product discovery. Researchers can identify novel bioactive compounds and unravel complex metabolic networks. Our platform aims to be a valuable asset for global researchers in microbial metabolomics.

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CRISPR-BCdb

CRISPR-BCdb is a specialized, curated database designed to support precision research in breast cancer using CRISPR-Cas9 technology. This comprehensive platform compiles breast cancer gene targets, associated single guide RNA (sgRNA) sequences, editing efficiencies, and primer information. The data is derived from powerful bioinformatic tools such as CHOPCHOP, Cas-OFFinder, and CRISPOR, streamlining the design and evaluation of CRISPR experiments. By bridging genomic data with therapeutic potential, CRISPR-BCdb empowers researchers to perform high-throughput functional screens, identify synthetic lethal interactions, and investigate mechanisms of drug resistance. Whether you're exploring gene function, developing targeted therapies, or advancing personalized oncology, CRISPR-BCdb serves as a vital resource for accelerating breast cancer research. Explore the database to discover guide RNAs tailored to breast cancer subtypes and unlock new possibilities in functional genomics.

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Tools


Phytochemical Activity Prediction Tool

Phytochemical Activity Prediction Tool, enables rapid in silico screening of phytochemicals by predicting their biological activities and ADME profiles from chemical structure. Users can input canonical SMILES notations to receive predictions across five major activity categories—antiviral, anti-inflammatory, antioxidant, antimicrobial, and anticancer—along with detailed ADME (Absorption, Distribution, Metabolism, and Excretion) properties. Powered by machine learning and trained on curated datasets, it supports efficient lead identification and reduces reliance on early experimental screening.

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Dihedral angles of reach aminoacid | Ramachandran Plot

This tool provides an interactive visualization of the phi (ϕ) and psi (ψ) dihedral angles of amino acid residues in proteins, mapped onto a Ramachandran plot. It enables users to analyze conformational constraints and permissible torsion angles for each amino acid, helping assess protein structure quality and stability. Particularly useful in structural biology and protein modeling, this tool supports validation of predicted or experimental protein conformations by identifying outliers and favored regions in backbone geometry.

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