CRISPR-BCdb

A Comprehensive CRISPR-Cas9 Target Gene Resource for Precision Breast Cancer Research

About CRSIPR-BCdb

CRISPR-BCdb is a specialized, curated database designed to support precision research in breast cancer using CRISPR-Cas9 technology. This comprehensive platform compiles breast cancer gene targets, associated single guide RNA (sgRNA) sequences, editing efficiencies, and primer information. The data is derived from powerful bioinformatic tools such as CHOPCHOP, Cas-OFFinder, and CRISPOR, streamlining the design and evaluation of CRISPR experiments. By bridging genomic data with therapeutic potential, CRISPR-BCdb empowers researchers to perform high-throughput functional screens, identify synthetic lethal interactions, and investigate mechanisms of drug resistance. Whether you're exploring gene function, developing targeted therapies, or advancing personalized oncology, CRISPR-BCdb serves as a vital resource for accelerating breast cancer research. Explore the database to discover guide RNAs tailored to breast cancer subtypes and unlock new possibilities in functional genomics.
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Guide RNAs for Breast Cancer-Associated Genes Available in the Database

TP53 PTEN CDH1 BRAC2 STK11 ATM BRCA1 CHEK2 VEGFA PIK3CA ERBB2 GATA3 CRP PALB2 MUC1 MYC NBN H19
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A Precision Resource for Breast Cancer Gene Targeting