Course details
OriGene Biosolutions is a premier life science research and training organization dedicated to advancing bioinformatics and data analysis. Tailored solutions for your bioinformatics needs.
Certificate Course in Computational Drug Designing
Level
Intermediate
Intermediate
Duration
1 Month | 8 hours per week
1 Month | 8 hours per week
Flexible Schedule
Learn from anywhere.
Learn from anywhere.
Modules
4
4
Capsote Project
Real-world project with publication.
Real-world project with publication.
Course Modules
Enroll Now- Drug discovery pipeline overview
- Target validation and selection
- Protein structure basics and PDB database
- Hands-on: Retrieve and analyze target protein structures
- Ligand databases: ZINC, PubChem
- Ligand preparation and energy minimization
- Virtual screening principles
- Hands-on: Perform virtual screening using AutoDock Vina
- Docking algorithms and scoring functions
- Protein-ligand interaction analysis (hydrogen bonds, hydrophobic)
- Visualization tools (PyMOL, Discovery Studio Visualizer)
- Hands-on: Docking and analyzing hits
- Drug-likeness rules (Lipinski’s Rule of Five)
- ADMET prediction tools (SwissADME, pkCSM)
- Lead compound optimization strategies
- Capstone project: Design and evaluate a lead compound
Course Overview
This course covers the fundamentals of rational drug design using bioinformatics and molecular modeling tools. Learners will explore target identification, ligand screening, docking, ADMET analysis, and lead optimization.
This course covers the fundamentals of rational drug design using bioinformatics and molecular modeling tools. Learners will explore target identification, ligand screening, docking, ADMET analysis, and lead optimization.
What You'll Learn
Drug discovery workflow and key concepts
Structure-based and ligand-based drug design
Molecular docking and virtual screening
ADMET prediction and drug-likeness
Lead optimization and hit validation
Who Can Register
UG/PG students, researchers, pharma professionals, and bioinformatics enthusiasts interested in drug discovery.
UG/PG students, researchers, pharma professionals, and bioinformatics enthusiasts interested in drug discovery.
Prerequisites
Basic knowledge of molecular biology and chemistry
Familiarity with protein structure concepts