Course details
OriGene Biosolutions is a premier life science research and training organization dedicated to advancing bioinformatics and data analysis. Tailored solutions for your bioinformatics needs.
Certificate Course in Computational Vaccine Designing
Level
Intermediate
Intermediate
Duration
1 Month | 8 hours per week
1 Month | 8 hours per week
Flexible Schedule
Learn from anywhere.
Learn from anywhere.
Modules
4
4
Capsote Project
Real-world project with publication.
Real-world project with publication.
Course Modules
Enroll Now- Types of vaccines: live, attenuated, subunit, epitope-based
- Antigen selection: conserved and surface-exposed proteins
- Databases: IEDB, UniProt, NCBI Protein
- Hands-on: Antigen sequence retrieval and basic analysis
- B-cell and T-cell epitope basics
- MHC Class I and II binding prediction (NetMHC, IEDB)
- Antigenicity (VaxiJen), allergenicity (AllerTOP), toxicity (ToxinPred)
- Hands-on: Predicting and filtering suitable epitopes
- Linker strategies and adjuvant addition
- Designing a multi-epitope construct
- 3D structure modeling (SWISS-MODEL, I-TASSER)
- Structure validation (Ramachandran, ERRAT)
- Immune response simulation (C-ImmSim tool)
- Codon optimization for expression (JCAT)
- Final mini-project: Design a theoretical vaccine against a selected pathogen
- Report preparation and result interpretation
Course Overview
This course introduces the principles and bioinformatics tools used in modern vaccine design. Learners will explore antigen selection, epitope mapping, population coverage analysis, and in silico immune response simulations. A capstone project involves designing a multi-epitope subunit vaccine using real pathogen data.
This course introduces the principles and bioinformatics tools used in modern vaccine design. Learners will explore antigen selection, epitope mapping, population coverage analysis, and in silico immune response simulations. A capstone project involves designing a multi-epitope subunit vaccine using real pathogen data.
What You'll Learn
Basics of immunoinformatics and vaccinology
Epitope prediction for B-cell and T-cell responses
Population coverage and allergenicity/toxicity screening
Multi-epitope vaccine construct design
Structural modeling and immune simulation
Who Can Register
UG/PG students, PhD researchers, academic faculty, and biotech professionals interested in immunology, infectious diseases, or vaccine development.
UG/PG students, PhD researchers, academic faculty, and biotech professionals interested in immunology, infectious diseases, or vaccine development.
Prerequisites
Basic understanding of immunology and molecular biology
Familiarity with protein sequences and bioinformatics databases
No prior coding required